Results of studies on nutrients supplementation in dementia
| Nutrients | Functions | Results |
|---|---|---|
| Omega-3 fatty acids20 | Anti-inflammatory effects | • Not improved cognition |
| Thiamine (vitamin B1)21 | Prevention of cognitive decline | • No reliable evidence |
| Vitamin B6, vitamin B12, folic acid22 | Reduce homecysteine levela | • No reliable evidence |
| Vitamin E23 | Antioxidative effect | • Not improved cognition |
| Selenium, copper24,25 | Antioxidative effect | • No reliable evidence |
| Vitamin D26 | Neuroprotective functions | • No reliable evidence |
aHyperhomocysteinaemia has been suggested as a cause or mechanism in the development of Alzheimer’s disease.