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Infection Control in Parenteral Nutrition Preparation and Compounding
정맥영양의 조제와 감염관리
J Clin Nutr 2018;10:31-37
Published online December 31, 2018
© 2018 Korean Society for Parenteral and Enteral Nutrition.

Ji Hyeong Choe, Jin Hee Baek, Yun Hee Jo, Yoon Sook Cho
최지형, 백진희, 조윤희, 조윤숙

Department of Pharmacy, Seoul National University Hospital, Seoul, Korea
서울대학교병원 약제부
Ji Hyeong Choe, https://orcid.org/0000-0002-9321-5953 Department of Pharmacy, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul 03080, Korea Tel: +82-2-2072-4992, Fax: +82-2-766-1443, E-mail: 30536@snuh.org
Received November 23, 2018; Revised November 29, 2018; Accepted December 2, 2018.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
 Abstract
Recently, in Korea, the importance of preparation and use of injectable drugs has been emphasized due to successive fatal accidents caused by injection infections. Parenteral nutrition (PN) has also been identified as a cause of infection. Cases of infection due to PN have been reported not only in Korea, but also abroad, and contamination occurs mainly during the preparation of PN. Because sterile preparation and compounding of injections are very important for infection control and patient safety, this article reviews the major guidelines outlined thus far. The Korea Ministry of Food and Drug Safety in 2006 published guidelines and the KSHP (Korean Society of Health-System Pharmacists) recently issued guidelines for the aseptic preparation of injections. In addition, as US guidelines, the ASHP (American Society of Health-System Pharmacists) guidelines and United States Pharmacopeia (USP) <797> are also reviewed. The recent guidelines published by the KSHP have significance in that they were adopted in accordance with the domestic reality, even though they conform to foreign guidelines, and are expected to be guidelines for hospital pharmacists performing aseptic preparation work. In addition, the Korea Ministry of Health and Welfare is considering appropriate guidelines for the safe management of medications, training staff for infection prevention and strengthening staff capacity. Furthermore, the gradual expansion of aseptic compounding facilities and human resources, as well as the provision of adequate medical costs are also considered. Based on the establishment and standardization of injectable drugs compounding guidelines for Korean hospitals, it is believed that if human resources and facilities are supported and medical charges are improved, it will be possible to expect the safer preparation and use of injections.
Keywords : Drug compounding, Environment, Controlled

 

December 2018, 10 (2)